Ownership Profile

Shareholder Breakdown
Shareholder Holders Values ($) % O/S Shares
Institution 241 1,620 97.51 64,363,359
Mutual Fund 282 866 51.42 33,942,422
Institutional Shareholder Rotation
Shareholder Holders Values Change ($) % O/S Shares Change
Buyers 113 236.28 14.25 9,406,919
Sellers 145 -187.90 11.30 -7,459,706
Net -- 48.38 2.95 1,947,213
Institutional Shareholder Concentration
Shareholder Values ($) % O/S Shares
Top 10 Inst. 894 54.25 35,811,599
Top 20 Inst. 1,169.05 70.57 46,582,767
Top 50 Inst. 1,435.98 86.63 57,179,688
Total Inst. 1,435.98 86.63 57,179,688
Institutional Shareholder Style
Shareholder Holders Values ($) % O/S Shares
Index 24 324 19.60 12,937,778
AggresGr 5 16 0.99 652,165
CoreGrowth 38 211 12.76 8,419,352
Growth 16 25 1.49 982,191
IncomeValue 3 6 0.34 225,757
Yield 3 1 0.03 21,566
BrokerDealer 15 16 0.94 620,748
GARP 22 441 26.67 17,601,637
HedgeFund 38 413 25.18 16,621,230
SectorSpecific 1 16 1.00 657,356
Specialty 2 5 0.28 187,888
CoreValue 21 64 3.74 2,469,773
DeepValue 7 12 0.74 486,745
Momentum 1 0 0.00 2,989
Top Holders: Institutional Investor
Holder Shares Held % O/S Shares Change Filing Date
Fidelity Management & Research Company 9,681,478 14.67 2,320,977 06/30/2017
The Vanguard Group, Inc. 5,223,345 7.91 -50,417 06/30/2017
BlackRock Institutional Trust Company, N.A. 3,842,784 5.82 -29,129 06/30/2017
Deerfield Management Company, L.P. 3,833,330 5.81 89,179 06/30/2017
Eagle Asset Management, Inc. 2,573,603 3.90 540,103 06/30/2017
Invesco Advisers, Inc. 2,392,605 3.62 -17,810 06/30/2017
Oracle Investment Management, Inc. 2,276,106 3.45 -445,800 06/30/2017
Gilder Gagnon Howe & Co. LLC 2,173,964 3.29 -26,255 07/31/2017
William Blair Investment Management, LLC 1,959,318 2.97 1,628,114 06/30/2017
Pennant Capital Management, LLC 1,855,066 2.81 -72,342 06/30/2017
Perceptive Advisors LLC 1,555,523 2.36 -262,666 06/30/2017
State Street Global Advisors (US) 1,340,810 2.03 104,007 06/30/2017
Waddell & Reed Investment Management Company 1,247,271 1.89 173,422 06/30/2017
Victory Capital Management Inc. 1,091,649 1.65 -322,450 06/30/2017
Cortina Asset Management L.L.C. 1,055,420 1.60 43,592 06/30/2017
Millennium Management LLC 971,623 1.47 591,391 06/30/2017
Burbank (Jeffrey H) 939,086 1.42 -6,000 04/20/2017
MFS Investment Management 920,998 1.40 330,723 06/30/2017
OppenheimerFunds, Inc. 879,326 1.33 -405,428 06/30/2017
Northern Trust Investments, Inc. 769,462 1.17 40,245 06/30/2017
Loomis, Sayles & Company, L.P. 689,146 1.04 -19,800 06/30/2017
Redmile Group, LLC 657,356 1.00 657,356 06/30/2017
Geode Capital Management, L.L.C. 615,151 0.93 20,168 06/30/2017
William Blair & Company, L.L.C. 598,671 0.91 -173,663 06/30/2017
Wells Capital Management Inc. 573,601 0.87 -354,442 06/30/2017
Portolan Capital Management, L.L.C. 492,188 0.75 -52,844 06/30/2017
Janus Henderson Investors 454,339 0.69 -19,291 06/30/2017
Norges Bank Investment Management (NBIM) 451,758 0.68 -81,500 12/31/2016
Marshall Wace LLP 444,618 0.67 444,618 06/30/2017
Altrinsic Global Advisors, LLC 426,300 0.65 -10,000 06/30/2017
Next Century Growth Investors, LLC 370,679 0.56 -174,801 06/30/2017
Two Sigma Investments, LP 354,302 0.54 -252,379 06/30/2017
Sectoral Asset Management Inc. 349,709 0.53 -154,859 06/30/2017
Nuveen LLC 343,687 0.52 11,203 06/30/2017
Charles Schwab Investment Management, Inc. 280,092 0.42 2,193 06/30/2017
Clough Capital Partners, LP 271,500 0.41 59,200 06/30/2017
BMO Global Asset Management 267,789 0.41 267,789 06/30/2017
Point72 Asset Management, L.P. 266,900 0.40 266,900 06/30/2017
Ghost Tree Capital, LLC 260,000 0.39 60,000 06/30/2017
Broadview Advisors, LLC 257,956 0.39 -143,400 06/30/2017
The Boston Company Asset Management, LLC 249,989 0.38 19,327 06/30/2017
Granahan Investment Management, Inc. 237,000 0.36 11,000 03/31/2017
D. E. Shaw & Co., L.P. 231,263 0.35 -88,963 06/30/2017
BlackRock Investment Management, LLC 222,388 0.34 -10,790 06/30/2017
Pura Vida Investments, LLC 221,685 0.34 -53,315 06/30/2017
Dafna Capital Management, LLC 216,119 0.33 0 06/30/2017
Rhenman & Partners Asset Management AB 213,901 0.32 60,000 06/30/2017
Susquehanna Financial Group, LLLP 195,373 0.30 182,005 06/30/2017
Henderson Geneva Capital Management 193,055 0.29 5,477 06/30/2017
Advisory Research, Inc. 190,406 0.29 78,563 03/31/2017

Ownership data is provided by Thomson Reuters, a third party service, and NxStage Medical, Inc. does not maintain or provide information directly to this service.